>>1
The matter and antimatter involved would be annihilated completely, being converted into pure energy in the amounts E=mc^2. The universe would not be at risk, but the immediate area could be damaged by the sudden presence of lots of energy. Therefore, antimatter could become a usable weapon in the future if we ever find a way to handle it - a minuscule part of the target would be annihilated, and the target would explode or just evaporate because of the extreme heat.
The total amounts of each form of matter matters (no pun intended) quite a bit in theoretical physics: for instance, certain systems predict that there must always be equal amounts of matter and antimatter in the universe, which appears to be contradicted by reality.