Clang is great to use compared to GCC. It compiles a lot faster and the impoved error messages are actually helpful.
On the other hand, the claimed performance advantages are against GCC 4.2 (the last version of GCC shipped by Apple), and GCC has improved a lot since then. It also doesn't work very well on non-Darwin platforms although support is improving for platforms other than Linux, where the GCC+glibc-mafia don't want any competition. As
>>2-kun pointed out, it doesn't support a whole lot of CPUs either.
As an OS X user I'm very happy with Clang and LLDB, and I'm sad every time I have to use GCC.