Anyway, when editing huge text data files the first choice pretty much always involves awk and sed. Those are really worth learning, unlike 70'S FREEWARES that are a royal pain to fit in a modern workflow and to use with a one-button mouse.
http://www.morphine.com/blog/?p=29
and ex is worth learning, too, since it's an enhanced version of ed. and once you've learned ex, learning vi is trivial.
also, your "modern" workflow is stuck in the 90s. ditch the mouse. just using the keyboard is a lot more efficient.