>>8
>>9
>>10
What happens is this - these people go through their lives as a man, so immersed in their nerdy genius that they never manage to venture outside their shell and seduce a woman. While their lives may be intellectually fulfilling, their sexual and emotional selves are lonely and depressing.
At some point, they start having sexual fantasies about being the woman they so desire but can never have. A beautiful woman, in fact. One that can charm and seduce anyone, even a pathetic nerd such as themselves. This eventually results in an overriding desire to actually be that woman.
Years of hormonal drugs, surgery and counselling later, and they eventually emerge as a Frankenstein's monster of padded breast and chopped cock.