I personally don't use drugs, or drink, and so I can't get really worked up about either side here.
I would also note, though, that given that the power and the resources of the government are not merely finite but, in these dire economic times shrinking year by year, it seems to me that it would be better for the government to restrict its expenditures to things more important than whether some pathetic thirty-year-old virgin loser who works part-time at Burger King is smoking a joint in his mom's basement, or whether some nineteen-year-old is drinking a beer at a frat party.
Like, maybe, I dunno, fixing the roads and delivering the mail, maybe, and preventing Osama bin Laden from killing us all. I'm just saying, here.