IRC Clients / Scripts

So.. out of all the IRC clients, scripts and addons, is there one setup that is commonly known as being pretty much awesome for most purposes?

I've been using mIRC + Anaconda for a while, and it's nice and tidy, but I hear Sysreset is pretty handy.

Any suggestions?

>>6
Irssi's serving scripts are quite poor
Then write a new one.