Cartoons that are depressing

What cartoons make you say "Holy crap that's depressing?" 

Noozles: Adventures in Koalawalla Land had a depressing ending. 

I thought everyone died in Care Bears the Movie II until I realized I had forgotten the ending.

>>20
My god yes. I remember I was getting into anime after I got out of highschool, and had run across Unico at the local video rental. (This was 1988, mind you.) So I'm sitting there watching it with my sister who was like three at the time, and at the end she turns to me and says, "The North Wind took Unico away..?" AND BURST INTO TEARS.

I felt like such a shit for renting it. T_T