Ultimate "feel good" anime

I'm looking for a good, funny "feel good" anime with adorable "so sweet it gave me diabetes" character(s), that leaves you with a "warm fuzzy feeling". It should be overwhelmingly positive, have a great happy ending (for ALL characters), and if it contains any love story, it would be nice if the male character was some kind of loser, or at least a generic nobody.
Oh, and the love story (if any) ends well (as in "they end up together at the end").

Any "feel good" anime that doesn't fit in my description is also welcome, as long as you describe it a bit. PLEASE don't refrain from telling the end. I actually want to know, as it is important in knowing if it actually is a "feel goog" anime or not. (I don't know if you can hide spoilers in here, but if not: SPOILER WARNING! you've been warned)

Mahoromatic. It may be Ecchi, but it is INCREDIBLE.

>>81
Looks like you have only watched the first season. They went Gaynax for the ending at full force.

BOTTLE FAIRY

GTO
Ranma ½
Love Hina

pani poni dash!

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Jungle Wa Itsume Hale Nochi Guu (it's mainly weird humor though)
Ranma ½ (at least the first few seasons)

>>66
Miyazaki actually didn't make Grave of the Fireflies.  He did make the TV series Mirai Shounen Conan which is pretty cool (though not particularly lighthearted).