Language Choice

Lets say my non-CS interests lay in Physics, Applied Math, and Mech E, should I focus on high-level languages (Java, Python, etc.) or lower languages (C, C++, and maybe Fortran-ish)?

Also, is there any point in learning the GUI aspect if they are mainly drag and drop with most IDE's (i.e. Netbeans)?

Use C#/.net then you can slap together crap without having to deal with neckbeards.