MouseEvents

I have a really weird problem.
I have an application (lets call it 'App A') that blocks simulated mouse events from 'App B'. How would I make 'App B's simulated mouse events invisible to 'App A' so that its not blocked.

Is there a way to talk to the hardware directly and make the simulated mouse events look like real events?

Sorry if this doesn't make sense.

authentic mouse movement to a location before clicking
Which completely does not happen all the time.

Consider: stylus pads, tablets, touchscreens.