Question regarding spoofing

There exists programs such as synner.pl or Xxpoof where one can send spoofed source packets to a target IP address. However, this is only limited to IP addresses. Is there any such way to do the same thing, but to a certain URL, rather than IP?

Say, for example, that example1.com and example2.com share the same IP address, but you only want to spoof an IP packet for example1.com, not example2.com. Would this be at all feasible?

>>11
Get wireshark, start capturing, login to your game, do some action, logout. Then login again, do same action, logout. Notice that packets for same action are different. Sending same packets won't give you the result you're expecting. Didn't fairX tell you that?