Do you think in 50 years that...

1. Drugs legislation will be overhauled? (as in partial/mass legalisation)

2. The fossil fuel crisis will be solved?

3. The way Israel is treated in the international, non-arab, community will be changed?

4. America will still be the world's leading superpower?

1: Partial legalisation. Drugs that really fuck you up like heroine and meth will still be illegal, while largely inconsequential drugs like marijuana and LSD will be legal and highly regulated.
2: Peak coal is over 100 years away, peak oil will make us poorer but the sky won't fall. 3rd world countries will have to stop overpopulating if they want to survive this.
3: I don't have a clue. Most likely Israel will still be a round and the middle east will be a little more open as it economically develops, though it's also possible some event will destabilise the entire region in the next 50 years, possibly aggravated by peak oil.
4: A 1st world China would in theory be more powerful than America, though peak oil will probably stunt their industrial growth and America has more space for population growth. America will probably still be at the #1 spot, especially if the NAU goes through, with Europe and China will be close behind and Russia still swinging it's dick around in the background.