Kilico

"Detective Akira Yusa sees his brother killed before his very eyes. Scanning the crowds of Shibuya, a woman catches his attention and his cop’s intuition tells him: “She did it!” He chases her through the streets into an abandoned building. She’s Kilico Sakaki, an assassin. And thus begins the trail of blood that links the two of them… "

Right at the start, the main character throws his bike through a oncoming car's windshield causing the car to explode. This series is awesome and manly.

http://manga.myran-san.com/index.php?dirpath=./Kotonoha/Kilico&order=0

The art style is odd...